王光辉 副研究员
电子邮件:wgh2891458@163.com
办公地址:科研楼1402
研究领域:植物与病原真菌互作
基本情况
王光辉,男,1983年8月生于河北任丘市,硕士生导师,副研究员。以禾谷镰刀菌和稻瘟菌为主要研究对象,利用分子生物学、生物信息学和生物化学等手段研究MAPK信号通路以及蛋白激酶等关键基因在病原真菌生长发育、胁迫应答和侵染致病过程中的重要生物学功能与分子机制,为设计和制定新的病害防控策略提供理论依据。先后主持国家自然科学基金面上项目和青年项目各1项,国家重点研发计划-子课题1项以及陕西省自然科学基础研究计划面上项目1项。研究成果在《Nature Microbiology》、《New Phytologist》、《PLoS Pathogens》、《International Journal of Biological Macromolecules》、《Environmental Microbiology》、《Molecular Plant-Microbe Interactions》、《Frontiers in Microbiology》等期刊发表SCI论文20余篇,其中第一作者或通讯作者10篇。
教育背景
2010.09-2015.06,西北农林科技大学植物病理学专业,获农学博士学位
2011.09-2013.09,美国普度大学植物病理系,访问学者
2007.09-2010.06,西北农林科技大学植物病理学专业,获农学硕士学位
2003.09-2007.06,西北农林科技大学植物保护专业,获农学学士学位
工作履历
2023.01~至今, 西北农林科技大学植物保护学院,副研究员
2018.09~2022.12,西北农林科技大学植物保护学院,助理研究员
2016.03-2016.09,台湾中兴大学植物病理系,访问学者
2015.11-2018.08,福建农林大学植物保护学院,博士后
教学工作
承担本科生《真菌与人》、《美国文化背景》等课程的教学工作
指导“国家级”大学生创新创业训练计划项目1项(评审结果:优秀)
科研项目
1. 国家自然科学基金面上项目:cAMP-PKA信号途径通过调控组蛋白乙酰化修饰参与禾谷镰刀菌产毒和致病的分子机制,2023/01-2026/12,54.00万元,主持。
2. 国家自然科学基金青年项目:禾谷镰刀菌SR蛋白调控有性生殖和致病性的分子机制,2019/01-2021/12,20.00万元,主持。
3. 国家重点研发计划-子课题:聚孢霉和内生细菌对小麦赤霉病生防机制的研究,2022/9-2026/12,50万元,主持。
4. 陕西省自然科学基础研究计划面上项目:小麦赤霉菌新型分泌小蛋白Ssp1功能和作用机理研究, 2020/01-2021/12,5万, 主持。
代表性论文
1. Yang Yang*, Huang Panpan*, Ma Yutong, Jiang Ruoxuan, Jiang Cong#, Wang Guanghui#. (2022). Insights into intracellular signaling network in Fusarium species. International Journal of Biological Macromolecules. 222: 1007–1014.
2. Zhu Jindong*, Hu Denghui, Liu Qianqian, Hou Rui, Xu Jin-Rong#, Wang Guanghui#. (2022). Stage-specific genetic interaction between FgYCK1 and FgBNI4 during vegetative growth and conidiation in Fusarium graminearum. International Journal of Molecular Sciences. 23(16): 9106.
3. Wang Guanghui*, Sun Peng*, Sun Zhongjuan, Zhu Jindong, Yu Dan, Tang Zhe, Wang Zonghua, Wang Chenfang#, Zheng Huawei#. (2022). Sgh1, an SR-like protein, is involved in fungal development, plant infection, and pre-mRNA processing in Fusarium graminearum. Journal of Fungi. 8(10): 1056.
4. Liang Jie*, Fu Xianhui, Hao Chaofeng, Bian Zhuyun, Liu Huiquan, Xu Jin-Rong, Wang Guanghui#. (2021) FgBUD14 is important for ascosporogenesis and involves both stage-specific alternative splicing and RNA editing during sexual reproduction. Environmental Microbiology. 23(9): 5052–5068
5. Ren Jingyi*, Li Chengliang, Gao Chengyun, Xu Jin-Rong, Jiang Cong, Wang Guanghui#. (2019) Deletion of FgHOG1 is suppressive to the mgv1 mutant by stimulating Gpmk1 activation and avoiding intracellular turgor elevation in Fusarium graminearum. Frontiers in Microbiology. 10: Article 1073.
6. Jiang Cong*, Cao Shulin, Wang Zeyi, Xu Huaijian, Liang Jie, Liu Huiquan, Wang Guanghui, Ding Mingyu, Wang Qinhu, Gong Chen, Feng Chanjing, Hao Chaofeng, Xu Jin-Rong#. (2019) An expanded subfamily of G-protein-coupled receptor genes in Fusarium graminearum required for wheat infection. Nature Microbiology. 4 (9): 1582-1591.
7. Wang Guanghui*, Sun Peng*, Gong Ziwen, Gu Lianfeng, Lou Yi, Zhang Lianhu, Su Li, Wang Baohua, Zhou Jie, Xu Jin-Rong, Wang Zonghua#, Zheng Wenhui#. (2018) Srk1 kinase, a SR protein-specific kinase, is important for sexual reproduction, plant infection and pre-mRNA processing in Fusarium graminearum. Environmental Microbiology. 20(9): 3261-3277.
8. Zhang Xiaojie*, Wang Guanghui*, Yang Chengdong, Huang Jun, Chen Xiaofeng, Zhou Jie, Li Guangpu, Norvienyeku Justice#, Wang, Zonghua#. (2017) A HOPS protein, MoVps41, is crucially important for vacuolar morphogenesis, vegetative growth, reproduction and virulence in Magnaporthe oryzae. Frontiers in Plant Science. 8: Article1091.
9. Wang Guanghui*, Li Guotian, Zhang Shijie, Jiang Cong, Qin Jun, Xu Jin-Rong#. (2015) Activation of the signaling mucin MoMsb2 and its functional relationship with Cbp1 in Magnaporthe oryzae. Environmental Microbiology. 17(8): 2969-2981.
10. Li Yang*, Wang Guanghui, Xu Jin-Rong#, Jiang Cong#. (2015) Penetration peg formation and invasive hyphae development require stage-specific activation of MoGTI1 in Magnaporthe oryzae. Molecular Plant-Microbe Interactions. 29(1): 36-45.
11. Qin Jun*, Wang Guanghui*, Jiang Cong, Xu Jin-Rong, Wang Chenfang#. (2015) Fgk3 glycogen synthase kinase is important for development, pathogenesis, and stress responses in Fusarium graminearum. Scientific Reports. 5: 8504.
12. Wang Guanghui*, Wang Chenfang*, Hou Rui, Zhou Xiaoying, Li Guotian, Zhang Shijie, Xu Jin-Rong#. (2012) The AMT1 arginine methyltransferase gene is important for plant infection and normal hyphal growth in Fusarium graminearum. PLoS One. 7(5): e38324.
13. Wang Chenfang*, Zhang Shijie, Hou Rui, Zhao Zhongtao, Zheng Qian, Xu Qijun, Zheng Dawei, Wang Guanghui, Gao Xuli, Ma Ji-Wen, Kistler H. Corby, Kang Zhensheng#, Xu Jin-Rong#. (2011) Functional analysis of the kinome of the wheat scab fungus Fusarium graminearum. PLoS Pathogens. 7(12): e1002460.
14. 刘倩倩*, 胡登辉*, 祝金栋, 王光辉#. (2022). 蛋白激酶FgBud32参与禾谷镰刀菌的生长发育、致病和胁迫应答. 菌物学报. 41(9): 1483-1497.
15. 孙忠娟*, 刘倩倩, 郭雨纤, 王光辉#, 王晨芳#. (2022). Analog-sensitive蛋白激酶研究系统在植物病原真菌中的建立. 生物技术通报. 38(11): 49-57.
16. 段凯莉*, 江聪, 王光辉#. (2021). 禾谷镰刀菌蛋白激酶研究进展. 生物技术进展. 11(5): 618-627.
17. 唐喆, 王光辉#. (2021). SEC11基因的HIGS表达载体构建及转基因水稻的抗病性分析. 西南农业学报. 34(12): 2572-2579