李朝飞 教授
电子邮件:zhaofeili@nwsuaf.edu.cn
联系电话:
办公地址:植保学院502
研究领域:昆虫病毒分子生物学
基本情况
李朝飞,男,1973年8月生,博士生导师,主要从事昆虫病毒分子生物学研究,先后主持国家自然科学基金项目4项,在杆状病毒入侵与出芽释放分子机理方面取得了一定的进展,研究成果在《Journal of Virology》《Virology》《Insect Biochemistry and Molecular Biology》等期刊发表。主讲《昆虫病毒学》课程。
教育背景
2000.09-2003.06,中山大学微生物学专业,获理学博士学位
1996.09-1999.06,沈阳农业大学昆虫学专业,获农学硕士学位
1992.09-1996.06,沈阳农业大学蚕学专业,获农学学士学位
工作履历
2011.11-至今,西北农林科技大学植物保护学院,教授
2005.12-2011.08,康奈尔大学Boyce Thompson研究所,博士后
2003.07-2005.11,中山大学生命科学学院,讲师
学术兼职
2019年-至今,环境昆虫学报,编委
所获荣誉
2011年,入选教育部“新世纪优秀人才支持计划”
教学工作
承担本科生《茶树病虫害防治学》,研究生《昆虫病毒学》课程。
科研项目
1.国家自然科学基金面上项目,杆状病毒AcMNPV募集宿主细胞Vps4调控核膜重构的分子机制,2022.01-2025.12,58万元。
代表性论文
1.Li Yuxiang, Ma Yixiang, Liu Xinrong, Guo Ya, Ji Ning, Li Zhaofei*. Genome sequence of a new densovirus infecting the leaf-curl plum aphid brachycaudus helichrysi. Archives of Virology. 2025,170(4): 65.
2.Bai Lisha, Sun Yu, Yue Xiaorong, Ji Ning, Yan Fanye, Yang Tian, Feng Guozhong, Guo Ya, Li Zhaofei*. Multifaceted interactions between host ESCRT-III and budded virus-related proteins involved in entry and egress of the baculovirus Autographa californica multiple nucleopolyhedrovirus. Journal of Virology. 2024, 98(2): 10.1128/jvi.01900-23.
3.Guo Jinliang, Li Shangrong, Bai Lisha, Zhao Huimin, Shang Wenyu, Zhong Zhaojun, Maimaiti Tuerxunjiang, Gao Xueyan, Ji Ning, Chao Yanjie, Li Zhaofei*, Du Dijun*. Structural transition of GP64 triggered by a pH-sensitive multi-histidine switch. Nature Communications. 2024, 15:7668.
4.Guo Ya, Zhao Yani, Yang Yang, Zhang Yahong, Li Yuying, Tian Honggang, Liu Tong-Xian, Li Zhaofei*. Plants affect the horizontal transmission of a new densovirus infecting the green peach aphid Myzus persicae by modulating honeydew production. Insect Science. 2024, 31(1):236-254.
5.Guo Ya, Ji Ning, Bai Lisha, Ma Juntian, Li Zhaofei*. Aphid viruses: A brief view of a long history. Frontiers in Insect Science. 2022, 2:846716.
6.Yue Qi, Li Jingfeng, Guo Ya, Yan Fanye, Liu Ximeng, Gary Blissard, Li Zhaofei*. Efficient entry of budded virions of Autographa californica multiple nucleopolyhedrovirus is dependent on dynamin, Rab5, and Rab11. Insect Biochemistry and Molecular Biology. 2020, 123:103409.
7.Liu Tingting, Li Yuying, Qiao Bin, Jiang Yuanyuan, Ji Ning, Li Zhaofei*. Disrupting the association of Autographa californica multiple nucleopolyhedrovirus Ac93 with cellular ESCRT-III/Vps4 hinders nuclear egress of nucleocapsids and intranuclear microvesicles formation. Virology, 2020, 541:85-100.
8.Yu Qianlong, Bai Lisha, Ji Ning, Yue Xiaorong, Jiang Yuanyuan, Li Zhaofei*. Critical residues and contacts within domain IV of Autographa californica multiple nucleopolyhedrovirus GP64 contribute to its refolding during membrane fusion. Journal of Virology, 2020, 94(19):e01105-20.
9.Yue Qi, Yu Qianlong, Yang Qi, Xu Ye, Guo Ya, Gary Blissard, Li Zhaofei*. Distinct roles of cellular ESCRT-I and ESCRT-III proteins in efficient entry and egress of budded virions of Autographa californica multiple nucleopolyhedrovirus. Journal of Virology, 2018, 92(1):e01636-17.
10.Guo Ya, Yue Qi, Gao Jinli, Wang Zhe, Chen Yun-Ru, Gary Blissard, Liu Tong-Xian, Li Zhaofei*. Roles of cellular NSF protein in entry and nuclear egress of budded virions of Autographa californica multiple nucleopolyhedrovirus. Journal of Virology, 2017, 91(20): e01111-17.
成果奖励
2004,荣获广东省科学技术奖一等奖(第五完成人)
2003,荣获蒲蛰龙学者科学基金奖